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DIGITAL HUMANITIES PROJECTS BY MEDIEVALIST ABIGAIL FIREY REACH SCHOLARS ACROSS THE GLOBE

By Vice President for Research Lisa Cassis Abigail Firey didn’t set out to blaze trails in digital humanities. But that’s exactly what has happened in her quest to get a grasp on the enormous corpus of unpublished manuscripts that are part of her work in medieval canon law. In this podcast Firey, the Theodore A. Hallam Professor (2017-2019) in the Department of History and a University Research Professor, recalls the chance encounter that changed her trajectory. “In 2007 a researcher at UK in the Classics Department, Ross Scaife—deeply beloved—ran into me outside the library.

UK Chemistry Researchers Awarded National Science Foundation Grant to Build a Battery Prototype

A team of scientists at the University of Kentucky and at the Massachusetts Institute of Technology have been awarded a National Science Foundation grant to develop a prototype of a battery utilizing chemical components prepared at UK. Professors Susan Odom and John Anthony (UK Chemistry) synthesized new organic compounds as donors and acceptors for a type of battery called a redox flow battery (RFB), currently of great interest for large-scale energy storage.

In Search of Novel Inhibitors of Metallo-β-lactamases

Metallo-β-lactamases (MBLs) are Zn(II)-containing enzymes produced by bacteria that inactivate all b-lactam containing antibiotics, including the carbapenems, which are antibiotics of last resort. While the MBLs have been studied for over 50 years, there are no clinical inhibitors for these enzymes. Therefore, there are few antibiotics available to treat bacterial infections caused by bacteria that produce a MBL. To address this problem, a multi-institution team of synthetic organic chemists (UC San Diego), medicinal chemists (UT Austin), microbiologists and MD’s (Case Western and the Cleveland VA), and structural biologists/biochemists (Miami University) teamed together to identify and develop new potential leads. In the seminar, recent results on a new inhibitor scaffold will be presented, along with biophysical studies on several other recently reported compounds in the literature.

 

Date:
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Location:
CP-114
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