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X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals

Christine Cardin will be presenting a Nietzel Visiting Distinguished Faculty Program Seminar titled, "X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals."

Abstract: Photoactive ruthenium polypyridyl complexes attract worldwide attention because of their potential applications in cancer chemotherapy and because they provide useful tools for studying the fundamentals of electron transfer in DNA. In this talk, the structures of several ruthenium complexes bound to several oligonucleotides will be described. The recent transient infrared spectroscopy (TRIR) study of the photooxidizing [Ru(TAP)2dppz]2+ complex crystallized with the decamer duplex d(TCGGCGCCGA)2 has provided an insight into the earliest steps in guanine photooxidation and hence, DNA damage.

Date:
-
Location:
CP - 114

22nd Annual Black Women's Conference

The University of Kentucky College of Arts & Sciences' African American and Africana Studies department presents:

22nd Annual Black Women's Conference

#SAYHERNAME, Making Black Women Visible in the Fight Against State Violence

April 27th - 30th, 2016

Breckenridge Hall, University of Kentucky

Lyric Theatre, Lexington KY

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